Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477873 | 0.93 | CTSS (0.34) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL6472444 | 0.80 | CTSS (0.35) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL5048251 | 0.75 | CTSL (0.42) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL6477869 | 0.71 | CTSL (0.42) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL3049273 | 0.68 | CTSK (0.47) | CTSSCTSKCTSLNFKB1NFKB2 | |
| SCHEMBL2367410 | 0.68 | CTSK (0.47) | CTSSCTSKCTSLNFKB1NFKB2 | |
| SCHEMBL66303 | 0.67 | CTSK (0.51) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL66302 | 0.67 | CTSK (0.51) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL1360500 | 0.67 | CTSK (0.51) | CTSSCTSKITGB3ITGA2BCTSL | |
| SCHEMBL3827244 | 0.66 | CTSS (0.43) | CTSSCTSKITGB3ITGA2BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |