Sugi Predict

Sugi Predict / Compounds / SCHEMBL66303

SCHEMBL66303

SCHEMBL66303

CC(C)(C)CC(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 7/20 0.51
▸ CTSS P25774 6/20 0.51
▸ PPARA Q07869 6/20 0.48
▸ PPARG P37231 5/20 0.48
▸ CTSL P07711 1/20 0.48
▸ CTSB P07858 1/20 0.48
▸ ACE P12821 1/20 0.47
▸ GRN P28799 1/20 0.46
▸ SORT1 Q99523 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA7 P43166 1/20 0.46
▸ PPARD Q03181 2/20 0.46
▸ MEN1 O00255 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ IDO1 P14902 1/20 0.44
▸ ITGB3 P05106 1/20 0.44
▸ ITGA2B P08514 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1360500 1.00 CTSK (0.51) CTSKCTSSPPARAPPARGCTSL
SCHEMBL66302 1.00 CTSK (0.51) CTSKCTSSPPARAPPARGCTSL
SCHEMBL16313976 0.93 CTSS (0.50) CTSKCTSSPPARAPPARGCTSL
SCHEMBL3818351 0.93 CTSS (0.50) CTSKCTSSPPARAPPARGCTSL
SCHEMBL3822699 0.93 CTSS (0.50) CTSKCTSSPPARAPPARGCTSL
SCHEMBL23879299 0.87 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL17203118 0.87 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL17203119 0.87 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL18980653 0.87 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL3820601 0.87 CTSS (0.61) CTSKCTSSCTSLCTSBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557853-A Leucine aminopeptidase fluorescent probe and preparation method and application thereof 南华大学附属南华医院 2023-01-03 — — CN claimed
CN-110256297-B Preparation method of N-Boc- (R) -2-amino-4, 4-dimethylpentanoic acid 爱斯特（成都）生物制药股份有限公司 2022-07-26 — — CN claimed
CN-110256297-A A kind of preparation method of N-Boc- (R) -2- amino -4,4- dimethyl valeric acid 爱斯特（成都）生物制药股份有限公司 2019-09-20 — — CN claimed
US-20260138988-A1 Spiropyrrolidine Derived Antiviral Agents ENANTA PHARMACEUTICALS INC (US) 2026-05-21 — — US disclosed
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 — — US disclosed
US-20260034084-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF NAVITOR PHARM INC (US) 2026-02-05 — — US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
US-12479854-B2 Spiropyrrolidine derived antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2025-11-25 — — US disclosed
US-12427130-B2 Modulators of Sestrin-GATOR2 interaction and uses thereof NAVITOR PHARMACEUTICALS, INC. (US) 2025-09-30 — — US disclosed
US-12378263-B2 Modulators of sestrin-GATOR2 interaction and uses thereof NAVITOR PHARMACEUTICALS, INC. (US) 2025-08-05 — — US disclosed
EP-3615019-B1 MODULATOR OF SESTRIN-GATOR2 INTERACTION FOR USE IN THE TREATMENT OF TREATMENT-RESISTANT DEPRESSION NAVITOR PHARM INC (US) 2025-06-04 — — EP disclosed
WO-2003029200-A2 COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2003-04-10 — — WO disclosed
EP-0669317-B1 Prolineamide derivatives MITSUBISHI CHEM CORP (JP) 2002-09-04 — — EP disclosed
EP-0460679-B1 Endothelin antagonistic peptide derivatives BANYU PHARMA CO LTD (JP) 1998-10-28 — — EP disclosed
US-5744487-A PROTEASE INHIBITORS MITSUBISHI CHEMICAL CORPORATION (JP) 1998-04-28 — — US disclosed
US-5691315-A CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-11-25 — — US disclosed
US-5470833-A Vasodilators, bronchodilators BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-11-28 — — US disclosed
EP-0669317-A1 Prolineamide derivatives Mitsubishi Chemical Corporation (JP) 1995-08-30 — — EP disclosed
US-5444152-A Vasolidator or bronchodilator BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-08-22 — — US disclosed
EP-0460679-A2 Endothelin antagonistic peptide derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1991-12-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138988-A1 Spiropyrrolidine Derived Antiviral Agents ACE, ACE2, TMPRSS2 CTSK 237/4885CTSS 45/4885PPARA 942/4885
US-20260034084-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF RICTOR, RPTOR, MTOR CTSK 4241/4885CTSS 3964/4885PPARA 3795/4885
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS CTRC, CTRL, CTSL CTSK 50/4885CTSS 7/4885PPARA 4811/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CTSK 4661/4885CTSS 4022/4885PPARA 2794/4885
US-12378263-B2 Modulators of sestrin-GATOR2 interaction and uses thereof GATD3, GABRR2, GABRR3 CTSK 4783/4885CTSS 4782/4885PPARA 3848/4885
US-12427130-B2 Modulators of Sestrin-GATOR2 interaction and uses thereof GATD3, GABRR2, GABRR3 CTSK 4783/4885CTSS 4782/4885PPARA 3848/4885
US-12479854-B2 Spiropyrrolidine derived antiviral agents ACE, ACE2, PKD1 CTSK 1623/4885CTSS 1063/4885PPARA 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.