Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051075 | 0.92 | EGFR (0.45) | CNR2RAB9AEGFRERBB2PPARG | |
| SCHEMBL5049918 | 0.92 | EGFR (0.45) | CNR2MEN1KMT2ASMN1; SMN2EGFR | |
| SCHEMBL5047503 | 0.89 | CNR2 (0.53) | CNR2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15617709 | 0.77 | GABBR2 (0.42) | GABBR2GABBR1BRD4HDAC4HDAC7 | |
| SCHEMBL5049914 | 0.76 | CA1 (0.39) | KMT2ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL5051019 | 0.76 | ALDH1A1 (0.48) | CNR2KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL746514 | 0.72 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL20682390 | 0.72 | L3MBTL1 (0.46) | MEN1KMT2ARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2337199 | 0.71 | PPARG (0.47) | MEN1KMT2AEGFRERBB2PPARG | |
| SCHEMBL11701644 | 0.71 | CYP2A6 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896401-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | Temple University of the Commonwealth System of Higher Education (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006091870-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2006-08-31 | — | — | WO | disclosed |