Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048643 | 0.89 | CNR2 (0.42) | CNR2KMT2AMEN1EGFRERBB2 | |
| SCHEMBL5049918 | 0.82 | EGFR (0.45) | CNR2KMT2AMEN1EGFRERBB2 | |
| SCHEMBL5051075 | 0.82 | EGFR (0.45) | CNR2EGFRERBB2TDP1CNR1 | |
| SCHEMBL828011 | 0.76 | KMT2A (0.56) | CNR2KMT2AMEN1EGFRERBB2 | |
| SCHEMBL15617698 | 0.75 | ABCB11 (0.47) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3237214 | 0.73 | NPC1 (0.60) | CNR2KMT2AMEN1UTS2RHPGD | |
| SCHEMBL5605863 | 0.73 | ALDH1A1 (0.46) | KMT2AMEN1EGFRUTS2RTDP1 | |
| SCHEMBL19984896 | 0.73 | TDP1 (0.51) | CNR2KMT2AMEN1UTS2RHPGD | |
| SCHEMBL4818974 | 0.72 | EGFR (0.56) | CNR2KMT2AMEN1EGFRERBB2 | |
| SCHEMBL171784 | 0.71 | LDHA (0.50) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896401-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | Temple University of the Commonwealth System of Higher Education (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2006091870-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2006-08-31 | — | — | WO | claimed |
| EP-1896401-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | Temple University of the Commonwealth System of Higher Education (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006091870-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2006-08-31 | — | — | WO | disclosed |