Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647350 | 0.84 | PTK2 (0.46) | UBE2MDCUN1D1PTK2ACACBSYK | |
| SCHEMBL1735359 | 0.83 | OPRM1 (0.46) | NEK2HDAC3HDAC1HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL1734487 | 0.83 | OPRM1 (0.45) | NEK2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1735223 | 0.81 | S1PR5 (0.52) | PTK2LMNA | |
| SCHEMBL3647478 | 0.81 | EGFR (0.44) | UBE2MDCUN1D1PTK2 | |
| SCHEMBL1735235 | 0.80 | LTA4H (0.52) | NEK2HDAC1HDAC6KMT2ASYK | |
| SCHEMBL13605487 | 0.80 | DRD3 (0.44) | HDAC3HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL1735211 | 0.78 | KDM4E (0.58) | MEN1KMT2ALMNA | |
| SCHEMBL1735247 | 0.78 | HRH3 (0.44) | HDAC3HDAC1HDAC2HDAC6DGAT1 | |
| SCHEMBL1735216 | 0.78 | HDAC3 (0.43) | NEK2HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-A2 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM, LLC (BM) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007038669-A2 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2007-04-05 | — | — | WO | disclosed |