Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048047 | 0.82 | FKBP1A (0.40) | L3MBTL1OPRM1OPRL1CYP1A2SMN1; SMN2 | |
| SCHEMBL4014338 | 0.81 | GBA1 (0.44) | BCHE | |
| SCHEMBL9283797 | 0.79 | GBA1 (0.47) | TSHRBCHE | |
| SCHEMBL9770467 | 0.78 | TERT (0.33) | ACE | |
| SCHEMBL3147824 | 0.78 | FKBP1A (0.40) | L3MBTL1ACESMN1; SMN2PTPN1 | |
| SCHEMBL15655931 | 0.77 | PTPN1 (0.34) | ACEOPRM1PTPN1TSHR | |
| SCHEMBL3911411 | 0.74 | ACE (0.39) | L3MBTL1ACEOPRM1SMN1; SMN2GAA | |
| SCHEMBL6865080 | 0.74 | KMT2A (0.40) | L3MBTL1TSHR | |
| SCHEMBL9342486 | 0.72 | L3MBTL1 (0.41) | L3MBTL1ACESMN1; SMN2TSHR | |
| SCHEMBL2686288 | 0.71 | PARP1 (0.34) | ACESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993998-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007065634-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-06-14 | — | — | WO | disclosed |