Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049189 | 0.82 | L3MBTL1 (0.37) | SMN1; SMN2CYP1A2L3MBTL1GAAOPRM1 | |
| SCHEMBL27425673 | 0.82 | FKBP1A (0.52) | FKBP1ABRD4CYP1A2HIF1AGAA | |
| SCHEMBL15656372 | 0.80 | FKBP1A (0.35) | FKBP1ABRD4CYP1A2HIF1ANPC1 | |
| SCHEMBL6869169 | 0.78 | BRD4 (0.50) | FKBP1ABRD4SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL19691863 | 0.75 | HRH3 (0.49) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL17596363 | 0.74 | HDAC3 (0.36) | FKBP1ACYP1A2HIF1AALDH1A1MEN1 | |
| SCHEMBL3105740 | 0.73 | BRD4 (0.44) | FKBP1ABRD4SMN1; SMN2CYP1A2HIF1A | |
| SCHEMBL6873102 | 0.72 | BRD4 (0.47) | BRD4RAB9AKMT2A | |
| SCHEMBL2687127 | 0.72 | PARP1 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7511684 | 0.71 | BRD4 (0.60) | BRD4SMN1; SMN2CYP1A2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993998-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-11-26 | — | — | EP | claimed |
| WO-2007065634-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-06-14 | — | — | WO | claimed |
| EP-1993998-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007065634-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-06-14 | — | — | WO | disclosed |