Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343638 | 1.00 | MAPT (0.55) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL2287032 | 0.89 | MEN1 (0.54) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL7685490 | 0.89 | MAPT (0.75) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL10076323 | 0.87 | MAPT (0.44) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL6339597 | 0.82 | MAPT (0.66) | MAPTCES2CES1CA1CA2 | |
| Dimethylamine SCHEMBL6342856 | 0.82 | MEN1 (0.52) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL6342854 | 0.82 | MEN1 (0.68) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL21679933 | 0.81 | CES2 (0.52) | MAPTCES2CES1CYP2A6CA1 | |
| SCHEMBL14596409 | 0.79 | CES2 (0.50) | MAPTCES2CES1CYP2A6CA1 | |
| SCHEMBL17547225 | 0.79 | CES2 (0.50) | CES2CES1CYP2A6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336894-A | One kind having AIE effect rigidity Conjugate macrocycle compound and its preparation and application | 东华大学 | 2019-02-15 | — | — | CN | claimed |
| US-12127473-B2 | Di-, tri- and tetraphenylindane derivates and their use in organic electronics | DOTTIKON ES HOLDING AG (CH) | 2024-10-22 | — | — | US | disclosed |
| CN-117551023-A | Preparation method and application of N-thio-phenyl phthalimide compound | 太原理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117447370-A | Preparation method of aggregation-induced emission material tetraaryl divinyl sulfide | 山西蓬勃健康科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2022-01-06 | — | — | US | disclosed |
| EP-3877357-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| CN-113365976-A | Diphenylindane, triphenylindane and tetraphenylindan derivatives and their use in organic devices | 多蒂肯独家合成控股公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109265311-B | Phenyl fluorene derivative and preparation method and application thereof | 上海兆维科技发展有限公司 | 2021-06-04 | — | — | CN | disclosed |
| EP-3650438-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| CN-109336894-A | One kind having AIE effect rigidity Conjugate macrocycle compound and its preparation and application | 东华大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-105272962-A | Synthetic method of 1,3-dithiane structure-containing polysubstituted olefin derivatives | UNIV LANZHOU | 2016-01-27 | — | — | CN | disclosed |
| US-7902744-B2 | Heteroionic junction light emitting electrochemical cell | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2011-03-08 | — | — | US | disclosed |
| US-20080191616-A1 | Polymer light-emitting devices based on interfaces enables by internally compensated doped conjugated ionomers | OREGON, UNIVERSITY OF | 2008-08-14 | — | — | US | disclosed |
| US-20080157662-A1 | Heteroionic junction light emitting electrochemical cell | OREGON, UNIVERSITY OF | 2008-07-03 | — | — | US | disclosed |
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5604224-A | NEURODEGENERATIVE DISORDERS | STERLING WINTHROP INC. (US) | 1997-02-18 | — | — | US | disclosed |
| US-5569655-A | Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1996-10-29 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0647641-A1 | Substituted heterocyclylisoquinolinium salts and compositions and methods of usethereof | STERLING WINTHROP INC. (US) | 1995-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | NR0B2, KCNJ2, TRRAP | MAPT 2927/4885HTT 1767/4885GFER 2895/4885 |
| US-12127473-B2 | Di-, tri- and tetraphenylindane derivates and their use in organic electronics | NR0B2, KCNJ2, TRRAP | MAPT 2927/4885HTT 1767/4885GFER 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.