Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150171 | 0.81 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5425653 | 0.81 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL34121 | 0.81 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL23907023 | 0.78 | MAPT (0.65) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL1028813 | 0.78 | MAPT (0.69) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL214204 | 0.78 | L3MBTL1 (0.36) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL7164529 | 0.77 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11119546 | 0.71 | MAPT (0.51) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4414748 | 0.70 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11056522 | 0.69 | MAPT (0.51) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149005-A2 | DYE COMPOSITION COMPRISING AN AMINOPYRAZOLOPYRIDINE OXIDATION BASE AND A SOURCE OF CARBONATE IONS | L'OREAL (FR) | 2008-12-11 | — | — | WO | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | disclosed |