SCHEMBL214204

SCHEMBL214204

CC1=C(c2ccccc2)N=NC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
GAA P10253 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 3/20 0.33
PDE4B Q07343 1/20 0.33
XDH P47989 1/20 0.33
KDM4E B2RXH2 1/20 0.33
APP P05067 1/20 0.33
CDK8 P49336 1/20 0.33
ACVR1 Q04771 1/20 0.33
TSHR P16473 1/20 0.33
MAOB P27338 1/20 0.33
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10990176 0.81 MAPT (0.40) MAPTLMNAGAAPDE4BKDM4E
SCHEMBL10979620 0.79 CYP2A6 (0.48) MAPTLMNAHTTKMT2AALDH1A1
SCHEMBL5049514 0.78 MAPT (0.48) L3MBTL1POLBMAPTLMNAHTT
SCHEMBL10359088 0.76 PDE4B (0.39) MAPTLMNAHTTGAANPC1
SCHEMBL10964297 0.74 LMNA (0.36) MAPTLMNAHTTGAANPC1
SCHEMBL10688416 0.74 MAPT (0.36) POLBMAPTLMNAHTTNPC1
SCHEMBL11519983 0.71 FGFR1 (0.43) LMNANPC1RAB9AALDH1A1KDM4E
SCHEMBL182947 0.70 PDE4B (0.42) L3MBTL1POLBMAPTLMNAHTT
SCHEMBL28035650 0.69 KIF11 (0.38) L3MBTL1POLBMAPTLMNAHTT
SCHEMBL7761880 0.68 TSHR (0.39) L3MBTL1POLBMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
EP-4731170-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE Wella Germany GmbH (DE) 2026-04-29 EP claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
CN-114423500-B Composition for dyeing keratin fibres and use thereof 莱雅公司 2025-02-25 CN claimed
WO-2025031867-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE WELLA GERMANY GMBH (DE) 2025-02-13 WO claimed
US-7172632-B2 Hair coloring compositions THE BOOTS COMPANY, PLC (GB) 2007-02-06 US claimed
EP-1670423-A1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2006-06-21 EP claimed
EP-1660022-A2 AGENT FOR COLOURING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2006-05-31 EP claimed
WO-2005044208-A1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-05-19 WO claimed
WO-2005032502-A2 AGENT FOR COLOURING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-04-14 WO claimed
US-20050039269-A1 Hair colouring compositions BOOTS COMPANY PLC, THE (GB) 2005-02-24 US claimed
EP-1429715-A2 HAIR COLOURING COMPOSITIONS The Boots Company PLC (GB) 2004-06-23 EP claimed
WO-2003015734-A2 HAIR COLOURING COMPOSITIONS THE BOOTS COMPANY PLC (GB) 2003-02-27 WO claimed
US-4927466-A AZO PIGMENTS PRODUCED BY REACTING AN AZO COMPOUND WITH A COUPLER IN THE PRESENCE OF A SURFACTANT BASF CORP. (US) 1990-05-22 US claimed
US-3939140-A Process for the preparation of a dyestuff consisting substantially of only unsymmetrical 1:2-chromium complex azo dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents PHOSPHO1, ALDH7A1, AASDHPPT L3MBTL1 2904/4885POLB 74/4885MAPT 2072/4885
US-12636241-B1 Method and composition for oxidative hair coloring POLB, DAO, ALPP L3MBTL1 1697/4885POLB 1/4885MAPT 2639/4885
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) DEGS1, SGMS1, FABP4 L3MBTL1 2790/4885POLB 2704/4885MAPT 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.