Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053124 | 0.88 | ALDH1A1 (0.41) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL278904 | 0.81 | DPP4 (0.65) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL50855 | 0.80 | APP (0.45) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL50628 | 0.79 | APP (0.48) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL607254 | 0.79 | DPP4 (0.69) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL21036842 | 0.79 | DPP4 (0.41) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL50464 | 0.78 | APP (0.43) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL3364399 | 0.75 | APP (0.55) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL51182 | 0.75 | APP (0.41) | DPP4APPCYP2A6CYP2E1CYP3A4 | |
| SCHEMBL11937048 | 0.74 | APP (0.62) | DPP4APPCYP2A6CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105199422-B | Sulfhydryl group-containing bithiophene benzoindoles dye as well as preparation method and application thereof | 北京科技大学 | 2017-05-10 | — | — | CN | claimed |
| CN-105199422-A | Sulfhydryl group-containing bithiophene benzoindoles dye as well as preparation method and application thereof | UNIV BEIJING SCIENCE & TECH | 2015-12-30 | — | — | CN | claimed |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
| CN-105199422-B | Sulfhydryl group-containing bithiophene benzoindoles dye as well as preparation method and application thereof | 北京科技大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-105199422-A | Sulfhydryl group-containing bithiophene benzoindoles dye as well as preparation method and application thereof | UNIV BEIJING SCIENCE & TECH | 2015-12-30 | — | — | CN | disclosed |
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
| EP-0759924-A1 | OLIGOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995030679-A1 | OLIGOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | DPP4 3131/4885APP 2001/4885CYP2A6 4407/4885 |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | DPP4 3525/4885APP 2264/4885CYP2A6 4362/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | DPP4 3131/4885APP 2001/4885CYP2A6 4407/4885 |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NLN, NME4, OAT | DPP4 635/4885APP 1243/4885CYP2A6 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.