Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50855 | 0.98 | APP (0.45) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL50725 | 0.88 | ALDH1A1 (0.46) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL50464 | 0.85 | APP (0.43) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL51182 | 0.83 | APP (0.41) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL4317739 | 0.82 | TNFRSF1A (0.39) | APPALDH1A1MAPTALDH1A3ALDH3A1 | |
| SCHEMBL50496 | 0.79 | DPP4 (0.49) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL607254 | 0.78 | DPP4 (0.69) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL3364399 | 0.76 | APP (0.55) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL3364398 | 0.75 | APP (0.70) | APPDPP4ALDH1A1MAPTCYP2E1 | |
| SCHEMBL13422457 | 0.75 | ALDH1A1 (0.42) | APPALDH1A1MAPTCYP3A4ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NLN, NME4, OAT | APP 1243/4885DPP4 635/4885ALDH1A1 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.