Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3419178 | 0.97 | ALDH1A1 (0.46) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| Bromide SCHEMBL962536 | 0.95 | CYP1A1 (0.47) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL5047353 | 0.79 | ADORA2B (0.33) | MAPK1ALDH1A1ADORA2BHTTRGS4 | |
| Bromide SCHEMBL3386795 | 0.78 | CYP1A1 (0.31) | CYP1A1CYP1B1MAPK1ADORA2BHTT | |
| Bromide SCHEMBL4940305 | 0.74 | CYP1A1 (0.48) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL4938578 | 0.71 | ALDH1A1 (0.59) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL19610233 | 0.70 | CYP1A1 (0.61) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL3384763 | 0.68 | CNR2 (0.63) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL3384765 | 0.68 | CNR2 (0.63) | SMN1; SMN2TSHRHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL3386346 | 0.67 | CNR1 (0.44) | SMN1; SMN2TSHRHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064699-A1 | Such as N-[3-(2-methoxyethyl)-1,3-thiazol-2(3H)-ylidene]adamantane-1-carboxamide; neuropathic, nociceptive and/or inflammatory pain; neuroprotection | ABBVIE INC. | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064699-A1 | Such as N-[3-(2-methoxyethyl)-1,3-thiazol-2(3H)-ylidene]adamantane-1-carboxamide; neuropathic, nociceptive and/or inflammatory pain; neuroprotection | OPRL1, OPRK1, OPRD1 | SMN1; SMN2 23/4885TSHR 2499/4885HSD17B10 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.