Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975892 | 0.84 | MEN1 (0.64) | KDM4EMAPTTDP1ATMCYP3A4 | |
| SCHEMBL27082946 | 0.80 | KDM4E (0.58) | KDM4EMAPTTDP1L3MBTL1ATM | |
| SCHEMBL2810003 | 0.79 | TSHR (0.53) | KDM4EMAPTTDP1HTR2AL3MBTL1 | |
| SCHEMBL9138641 | 0.78 | KDM4E (0.66) | KDM4EMAPTTDP1ATMCYP3A4 | |
| SCHEMBL18503019 | 0.77 | KMT2A (0.47) | KDM4EMAPTTDP1HTR2AL3MBTL1 | |
| SCHEMBL10645463 | 0.77 | KMT2A (0.53) | KDM4EMAPTTDP1HTR2AL3MBTL1 | |
| SCHEMBL11299984 | 0.77 | KDM4E (0.47) | KDM4EMAPTTDP1ATMKMT2A | |
| SCHEMBL8114346 | 0.76 | KDM4E (1.00) | KDM4EMAPTTDP1CYP3A4KMT2A | |
| SCHEMBL12852124 | 0.76 | MEN1 (0.61) | KDM4EMAPTTDP1L3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL3620025 | 0.75 | MAPT (0.62) | KDM4EMAPTTDP1ATMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124637-B2 | Anthra [1, 2-d]imidazole-6,11-dione derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-02-28 | — | — | US | disclosed |
| US-8124637-B2 | Anthra [1, 2-d]imidazole-6,11-dione derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-02-28 | — | — | US | disclosed |
| US-20110207719-A1 | Novel Anthra [1, 2-d]imidazole-6,11-dione Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| US-20110207719-A1 | Novel Anthra [1, 2-d]imidazole-6,11-dione Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| EP-2000803-A1 | Nanoparticles with Polymer Shells | Nanosphere, Inc. (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1135682-B1 | NANOPARTICLES WITH POLYMER SHELLS | NANOSPHERE INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1135682-A4 | NANOPARTICLES WITH POLYMER SHELLS | NANOSPHERE INC (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1135682-A1 | NANOPARTICLES WITH POLYMER SHELLS | Nanosphere, Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000033079-A1 | NANOPARTICLES WITH POLYMER SHELLS | NANOSPHERE, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207719-A1 | Novel Anthra [1, 2-d]imidazole-6,11-dione Derivatives, Preparation Method and application thereof | TERT, ACIN1, AK2 | KDM4E 1004/4885MAPT 3490/4885TDP1 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.