SCHEMBL1975892

SCHEMBL1975892

CN(C)Cc1c2ccccc2c(CN(C)C)c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
TNNI3 P19429 1/20 0.64
TNNT2 P45379 1/20 0.64
TNNC1 P63316 1/20 0.64
MAPT P10636 2/20 0.57
CYP3A4 P08684 2/20 0.57
KDM4E B2RXH2 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
CHRM2 P08172 1/20 0.52
CHRNA7 P36544 1/20 0.52
CYP2D6 P10635 3/20 0.47
CYP2C19 P33261 3/20 0.47
HSD17B10 Q99714 1/20 0.47
TAAR1 Q96RJ0 1/20 0.44
HTR6 P50406 1/20 0.42
POLB P06746 1/20 0.42
CYP1A2 P05177 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12852124 0.91 MEN1 (0.61) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL5049991 0.84 KDM4E (0.61) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL15158394 0.79 MAPT (0.51) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL2519816 0.79 MEN1 (1.00) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL1720604 0.76 MAPT (0.64) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL12293604 0.76 ALDH1A1 (0.55) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL10063866 0.75 KMT2A (0.60) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL14890983 0.74 ALDH1A1 (0.42) MEN1KMT2ATNNI3TNNT2TNNC1
SCHEMBL9138641 0.74 KDM4E (0.66) MEN1KMT2ATNNI3TNNT2TNNC1
2-Methyl Gramine SCHEMBL2519973 0.74 MAPT (1.00) MEN1KMT2AMAPTCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US disclosed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-20260110028-A1 NUCLEOTIDE ANALOGS AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-04-23 US disclosed
US-12595508-B2 Nucleotide cleavable linkers and uses thereof Singular Genomics Systems, Inc. (US) 2026-04-07 US disclosed
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-03-26 US disclosed
US-12577271-B2 Modified nucleotides and uses thereof Singular Genomics Systems, Inc. (US) 2026-03-17 US disclosed
WO-2022072374-A1 LIGHT-CONTROLLED BIOORTHOGONAL TETRAZINE LIGATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-07 WO disclosed
US-11266673-B2 Nucleotide derivatives and methods of use thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-03-08 US disclosed
US-8765894-B2 Norbornene-type polymers having quaternary ammonium functionality PROMERUS, LLC (US) 2014-07-01 US disclosed
US-8765893-B2 Norbornene-type polymers having quaternary ammonium functionality PROMERUS, LLC (US) 2014-07-01 US disclosed
US-20110244368-A1 NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY PROMERUS LLC (US) 2011-10-06 US disclosed
US-20110143260-A1 NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY PROMERUS LLC (US) 2011-06-16 US disclosed
US-20100260903-A1 DEVICE FOR THE QUALIFICATION OF COOKING OILS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2010-10-14 US disclosed
EP-2104854-A1 DEVICE FOR THE QUALIFICATION OF COOKING OILS, AND METHODS 3M Innovative Properties Company (US) 2009-09-30 EP disclosed
WO-2008086137-A1 DEVICE FOR THE QUALIFICATION OF COOKING OILS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ MEN1 3513/4885KMT2A 308/4885TNNI3 3698/4885
US-12595508-B2 Nucleotide cleavable linkers and uses thereof NSUN2, CCRL2, NOP2 MEN1 4378/4885KMT2A 2804/4885TNNI3 84/4885
US-12577271-B2 Modified nucleotides and uses thereof NUDT1, NSUN2, CCRL2 MEN1 2476/4885KMT2A 2809/4885TNNI3 496/4885
US-12637489-B2 Silicon containing modified nucleotide analogs NSUN2, POLR2H, POLH MEN1 2394/4885KMT2A 2375/4885TNNI3 434/4885
US-20260110028-A1 NUCLEOTIDE ANALOGS AND USES THEREOF POLL, POLB, POLN MEN1 3638/4885KMT2A 1209/4885TNNI3 2537/4885
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF POLB, POLM, POLRMT MEN1 1571/4885KMT2A 1696/4885TNNI3 3769/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM MEN1 2077/4885KMT2A 755/4885TNNI3 4481/4885
US-11266673-B2 Nucleotide derivatives and methods of use thereof POLRMT, NSUN2, NUDT1 MEN1 3223/4885KMT2A 1863/4885TNNI3 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.