SCHEMBL5050260

SCHEMBL5050260

OC[C@@H]1[C@H](CO)[C@@H]2C=C[C@H]1C2

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480357 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL7139438 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL16705142 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL16704820 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL14619008 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL19619081 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL659852 1.00 USP2 (0.33) USP2TSHRHTTHSD17B10ALDH1A1
SCHEMBL13370560 0.87 USP2 (0.32) USP2TSHRHTTHSD17B10
SCHEMBL2032546 0.84 ALDH1A1 (0.32) ALDH1A1
SCHEMBL13346637 0.84 ALDH1A1 (0.32) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230098612-A1 SULFUR-BASED FUNCTIONAL PREPOLYMERS FOR POLYURETHANES AND POLYMERIC MATERIALS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-03-30 US claimed
EP-3508510-A1 CONTACT-KILLING, QAC FUNCTIONALIZED THERMOPLASTIC POLYURETHANE FOR CATHETER APPLICATIONS The University of Akron (US) 2019-07-10 EP claimed
US-20190106525-A1 CONTACT-KILLING, QAC FUNCTIONALIZED THERMOPLASTIC POLYURETHANE FOR CATHETER APPLICATIONS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2019-04-11 US claimed
US-12534565-B2 Sulfur-based functional prepolymers for polyurethanes and polymeric materials ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-01-27 US disclosed
US-20230272152-A1 NOVEL POLYURETHANES AND THEIR USE IN PHARMACEUTICAL DOSAGE FORMS BASF SE (DE) 2023-08-31 US disclosed
EP-4225821-A1 NOVEL POLYURETHANES AND THEIR USE IN PHARMACEUTICAL DOSAGE FORMS BASF SE (DE) 2023-08-16 EP disclosed
US-20230098612-A1 SULFUR-BASED FUNCTIONAL PREPOLYMERS FOR POLYURETHANES AND POLYMERIC MATERIALS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-03-30 US disclosed
WO-2022073950-A1 NOVEL POLYURETHANES AND THEIR USE IN PHARMACEUTICAL DOSAGE FORMS BASF SE (DE) 2022-04-14 WO disclosed
US-11155668-B2 Contact-killing, QAC functionalized thermoplastic polyurethane for catheter applications THE UNIVERSITY OF AKRON (US) 2021-10-26 US disclosed
WO-2021158730-A1 SULFUR-BASED FUNCTIONAL PREPOLYMERS FOR POLYURETHANES AND POLYMERIC MATERIALS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2021-08-12 WO disclosed
EP-3508510-A1 CONTACT-KILLING, QAC FUNCTIONALIZED THERMOPLASTIC POLYURETHANE FOR CATHETER APPLICATIONS The University of Akron (US) 2019-07-10 EP disclosed
US-20190106525-A1 CONTACT-KILLING, QAC FUNCTIONALIZED THERMOPLASTIC POLYURETHANE FOR CATHETER APPLICATIONS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2019-04-11 US disclosed
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US disclosed
WO-2005014693-A1 METHOD OF CROSSLINKING INTRINSICALLY CONDUCTIVE POLYMERS OR INTRINSICALLY CONDUCTIVE POLYMER PRECURSORS AND THE ARTICLES OBTAINED THEREFROM UNIVERSITY OF CONNECTICUT (US) 2005-02-17 WO disclosed
US-20040242792-A1 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom CONNECTICUT, THE UNIVERSITY OF 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534565-B2 Sulfur-based functional prepolymers for polyurethanes and polymeric materials CBS, ACSL3, EIF3L USP2 1895/4885TSHR 3815/4885HTT 1532/4885
US-11155668-B2 Contact-killing, QAC functionalized thermoplastic polyurethane for catheter applications QARS1, DDC, AADAC USP2 923/4885TSHR 3862/4885HTT 3189/4885
US-20190106525-A1 CONTACT-KILLING, QAC FUNCTIONALIZED THERMOPLASTIC POLYURETHANE FOR CATHETER APPLICATIONS QARS1, DDC, AADAC USP2 923/4885TSHR 3862/4885HTT 3189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.