Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053418 | 0.84 | MMP1 (0.43) | CPB1CPB2ECE1MMP1MMP3 | |
| SCHEMBL1524821 | 0.84 | CTSK (0.52) | ECE1MME | |
| SCHEMBL5055000 | 0.84 | ERAP2 (0.45) | CPB1CPB2ECE1FOLH1MME | |
| SCHEMBL5050396 | 0.82 | ERAP2 (0.44) | CPB1CPB2ECE1FOLH1MME | |
| SCHEMBL15135507 | 0.82 | ERAP2 (0.44) | CPB1CPB2ECE1FOLH1MME | |
| SCHEMBL5050215 | 0.82 | ERAP2 (0.53) | CPB1CPB2ECE1MMP1MMP3 | |
| SCHEMBL28752252 | 0.81 | LNPEP (0.46) | CPB1CPB2ECE1FOLH1TLR2 | |
| SCHEMBL1711293 | 0.80 | ERAP2 (0.43) | CPB1CPB2ECE1FOLH1MME | |
| SCHEMBL1711305 | 0.80 | ERAP2 (0.43) | CPB1CPB2ECE1FOLH1MME | |
| SCHEMBL5049005 | 0.80 | ERAP2 (0.43) | CPB1CPB2ECE1FOLH1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522249-C | Elongated multiple spacers in activatable prodrugs | SINTAGAR B V (NL) | 2009-08-05 | — | — | CN | claimed |
| EP-1370298-B1 | ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS | SYNTARGA BV (NL) | 2008-10-08 | — | — | EP | claimed |
| CN-1511044-A | Elogated and multiple spacers in activatible prodrugs | — | 2004-07-07 | — | — | CN | claimed |
| CN-100522249-C | Elongated multiple spacers in activatable prodrugs | SINTAGAR B V (NL) | 2009-08-05 | — | — | CN | disclosed |