Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070304 | 0.87 | L3MBTL1 (0.46) | MAPTMAOAMAOBL3MBTL1TDP1 | |
| SCHEMBL2243335 | 0.87 | MAOA (0.44) | MAPTMAOAMAOBL3MBTL1TDP1 | |
| SCHEMBL656697 | 0.81 | MAOA (0.42) | MAPTABCC4MAOAMAOBL3MBTL1 | |
| SCHEMBL1678464 | 0.81 | MAOA (0.45) | MAPTMAOAMAOBLMNAALDH1A1 | |
| SCHEMBL5050430 | 0.80 | MAPT (0.47) | MAPTABCC4MAOAMAOBL3MBTL1 | |
| SCHEMBL29217264 | 0.73 | MAPT (0.71) | MAPTABCC4L3MBTL1TDP1LMNA | |
| SCHEMBL28345621 | 0.72 | MAOA (0.39) | MAOAMAOBTDP1ALDH1A1KMT2A | |
| SCHEMBL7551879 | 0.71 | TDP1 (0.74) | MAPTL3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL12854830 | 0.71 | MAPT (0.68) | MAPTABCC4L3MBTL1TDP1LMNA | |
| SCHEMBL28052282 | 0.71 | TDP1 (0.74) | MAPTL3MBTL1TDP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904557-A1 | ALDEHYDE FUNCTIONAL SILOXANES | Dow Corning Corporation (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011465-A1 | ALDEHYDE FUNCTIONAL SILOXANES | DOW CORNING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |