Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656697 | 0.80 | MAOA (0.42) | MAPTABCC4L3MBTL1LMNATDP1 | |
| SCHEMBL5050428 | 0.80 | MAPT (0.41) | MAPTABCC4L3MBTL1LMNATDP1 | |
| SCHEMBL29217264 | 0.79 | MAPT (0.71) | MAPTABCC4L3MBTL1LMNATDP1 | |
| SCHEMBL12854830 | 0.77 | MAPT (0.68) | MAPTABCC4L3MBTL1LMNATDP1 | |
| SCHEMBL1678464 | 0.76 | MAOA (0.45) | MAPTLMNAALDH1A1POLBMAOA | |
| SCHEMBL13070304 | 0.76 | L3MBTL1 (0.46) | MAPTL3MBTL1LMNATDP1HDAC3 | |
| SCHEMBL7217517 | 0.74 | L3MBTL1 (0.54) | MAPTL3MBTL1LMNATDP1CES2 | |
| SCHEMBL1899361 | 0.72 | AKT1 (0.47) | MAPTL3MBTL1LMNATDP1CES2 | |
| Benzoic Acid SCHEMBL10962811 | 0.72 | L3MBTL1 (0.50) | MAPTABCC4L3MBTL1LMNATDP1 | |
| SCHEMBL7984999 | 0.72 | MAOA (0.52) | MAPTL3MBTL1LMNATDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904557-A1 | ALDEHYDE FUNCTIONAL SILOXANES | Dow Corning Corporation (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011465-A1 | ALDEHYDE FUNCTIONAL SILOXANES | DOW CORNING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |