Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008266 | 0.95 | ALDH1A1 (0.51) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL5050844 | 0.88 | ALDH1A1 (0.45) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL3629060 | 0.76 | ALDH1A1 (0.77) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL8404683 | 0.73 | LMNA (0.52) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL8404684 | 0.73 | ALDH1A1 (0.56) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL1909276 | 0.73 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL15221517 | 0.73 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL3001144 | 0.72 | ALDH1A1 (0.63) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL3001574 | 0.72 | CA12 (0.58) | ALDH1A1TSHRMAPK1BLMPMP22 | |
| SCHEMBL15947383 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNASLC22A2SLC22A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | disclosed |