SCHEMBL8404683

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5050844	0.88	ALDH1A1 (0.45)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	SCHEMBL8404684	0.85	ALDH1A1 (0.56)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	SCHEMBL19634425	0.85	ALDH1A1 (0.73)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	SCHEMBL8404664	0.84	HDAC3 (0.61)	TSHRHDAC3HDAC6NCOR2BLM
	SCHEMBL13496897	0.83	LMNA (0.48)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	SCHEMBL15947383	0.82	ALDH1A1 (0.50)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	SCHEMBL13496890	0.82	LMNA (0.50)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	Hydrochloric Acid SCHEMBL11907494	0.82	HDAC3 (0.59)	TSHRHDAC3HDAC6NCOR2BLM
	SCHEMBL5009757	0.81	ALDH1A1 (0.60)	LMNAALDH1A1TSHRSLC22A2SLC22A1
	SCHEMBL14038077	0.79	HDAC3 (0.49)	LMNAALDH1A1TSHRSLC22A2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.