SCHEMBL5052242

SCHEMBL5052242

C=[C]C(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 3/20 0.61
PTPN1 P18031 3/20 0.61
PPARG P37231 3/20 0.61
PPARD Q03181 3/20 0.61
PPARA Q07869 3/20 0.61
CYP1A2 P05177 2/20 0.61
MAPT P10636 2/20 0.61
CYP2C19 P33261 2/20 0.61
BLM P54132 2/20 0.61
HSD17B10 Q99714 2/20 0.61
FABP4 P15090 2/20 0.61
FAAH O00519 2/20 0.61
KMT2A Q03164 2/20 0.61
F7 P08709 2/20 0.61
F3 P13726 2/20 0.61
DUSP3 P51452 2/20 0.61
GMNN O75496 1/20 0.61
USP2 O75604 1/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8814525 0.81 TERT (0.61) TERTPTPN1PPARGPPARDPPARA
SCHEMBL32674589 0.81 FAAH (0.64) TERTPTPN1PPARGPPARDPPARA
Oleic Acid SCHEMBL31462131 0.81 PPARG (0.85) TERTPTPN1PPARGPPARDPPARA
SCHEMBL3065252 0.81 TERT (0.61) TERTPTPN1PPARGPPARDPPARA
SCHEMBL9745146 0.81 TERT (0.61) TERTPTPN1PPARGPPARDPPARA
SCHEMBL19011847 0.81 TERT (0.61) TERTPTPN1PPARGPPARDPPARA
SCHEMBL220791 0.79 TERT (0.68) TERTPTPN1PPARGPPARDPPARA
SCHEMBL9228821 0.79 TERT (0.68) TERTPTPN1PPARGPPARDPPARA
SCHEMBL1669629 0.79 TERT (0.68) TERTPTPN1PPARGPPARDPPARA
SCHEMBL10521045 0.79 TERT (0.68) TERTPTPN1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080253960-A1 Lipoprotein-Based Nanoplatforms THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CENTER FOR TECHNOLOGY TRANSFER (US) 2008-10-16 US disclosed
EP-1778298-A2 LIPOPROTEIN NANOPLATFORMS The Trustees of The University of Pennsylvania (US) 2007-05-02 EP disclosed
WO-2006073419-A2 LIPOPROTEIN NANOPLATFORMS ZHENG GANG (US) 2006-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080253960-A1 Lipoprotein-Based Nanoplatforms LDLR, APOL1, LRP6 TERT 3976/4885PTPN1 193/4885PPARG 496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.