Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059815 | 0.85 | TYR (0.40) | TYRTHRATHRBHRH3ALDH1A1 | |
| SCHEMBL15492944 | 0.77 | MAPK1 (0.44) | ALDH1A1NPSR1MAPTKMT2AHPGD | |
| SCHEMBL5056590 | 0.73 | HPGD (0.39) | THRBALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL5236317 | 0.72 | THRB (0.35) | THRATHRBALDH1A1KDM4ENPSR1 | |
| SCHEMBL5055747 | 0.72 | KDM4E (0.40) | THRATHRBALDH1A1KDM4ENPSR1 | |
| SCHEMBL5235448 | 0.70 | DPP4 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL16350295 | 0.67 | CYP3A4 (0.36) | THRATHRBALDH1A1MAPTLMNA | |
| SCHEMBL15604205 | 0.66 | PGR (0.41) | THRATHRBHRH3ALDH1A1KDM4E | |
| SCHEMBL5239820 | 0.64 | CASR (0.36) | THRATHRBALDH1A1KDM4ENPSR1 | |
| SCHEMBL9915359 | 0.64 | COMT (0.40) | TYRALDH1A1MAPTPDE4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637705-B1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING S COLLEGE LONDON (GB) | 2017-03-29 | — | — | EP | disclosed |
| US-9138495-B2 | Conjugates and their uses in molecular imaging | KING'S COLLEGE LONDON (GB) | 2015-09-22 | — | — | US | disclosed |
| US-20140056810-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING'S COLLEGE LONDON (GB) | 2014-02-27 | — | — | US | disclosed |
| WO-2012063028-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING'S COLLEGE LONDON (GB) | 2012-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140056810-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | PAICS, FOLH1, DSTYK | TYR 3833/4885THRA 2044/4885THRB 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.