Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.34 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481775 | 0.82 | ALDH2 (0.41) | ALDH1A1MAPTELANESMN1; SMN2 | |
| SCHEMBL8268655 | 0.78 | THRA (0.41) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL13413902 | 0.77 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL2115557 | 0.75 | IDH1 (0.50) | ALDH1A1LMNAMAPTNPC1HPGD | |
| SCHEMBL17403940 | 0.75 | KDM4E (0.32) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL14065445 | 0.74 | PTGS1 (0.35) | KDM4EALDH1A1LMNAMAPTTHRB | |
| SCHEMBL14640654 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNANPC1HPGD | |
| SCHEMBL5056587 | 0.72 | TYR (0.40) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7749630 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1THRATHRBELANE | |
| SCHEMBL13423056 | 0.71 | MAPT (0.42) | KDM4EALDH1A1LMNAMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637705-B1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING S COLLEGE LONDON (GB) | 2017-03-29 | — | — | EP | disclosed |
| US-20170066754-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-9572813-B2 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9138495-B2 | Conjugates and their uses in molecular imaging | KING'S COLLEGE LONDON (GB) | 2015-09-22 | — | — | US | disclosed |
| US-20150202208-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| US-20140056810-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING'S COLLEGE LONDON (GB) | 2014-02-27 | — | — | US | disclosed |
| WO-2012063028-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING'S COLLEGE LONDON (GB) | 2012-05-18 | — | — | WO | disclosed |
| US-20100098640-A1 | Multidentate Pyrone-Derived Chelators for Medicinal Imaging and Chelation | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2010-04-22 | — | — | US | disclosed |
| US-20080076740-A1 | Antiviral compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
| WO-2007014352-A2 | ANTIVIRAL PHOSPHONATE CONJUGATES FOR INHIBITION OF HIV | GILEAD SCIENCES, INC. (US) | 2007-02-01 | — | — | WO | disclosed |
| WO-2007002109-A2 | MULTIDENTATE PYRONE-DERIVED CHELATORS FOR MEDICINAL IMAGING AND CHELATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202208-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | KDM4E 382/4885ALDH1A1 424/4885LMNA 2945/4885 |
| US-20140056810-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | PAICS, FOLH1, DSTYK | KDM4E 2915/4885ALDH1A1 2141/4885LMNA 3138/4885 |
| US-20170066754-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | KDM4E 382/4885ALDH1A1 424/4885LMNA 2945/4885 |
| US-20100098640-A1 | Multidentate Pyrone-Derived Chelators for Medicinal Imaging and Chelation | DNM1, BET1, FOLH1 | KDM4E 560/4885ALDH1A1 3797/4885LMNA 2576/4885 |
| US-20080076740-A1 | Antiviral compounds | EIF2AK2, MAVS, ITPA | KDM4E 2067/4885ALDH1A1 4716/4885LMNA 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.