SCHEMBL5057741

SCHEMBL5057741

CCCCCOC(=O)C1(C)C=CC(C)=CC1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.40
NAAA Q02083 1/20 0.40
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
PSEN1 P49768 3/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
EPHX1 P07099 1/20 0.35
PRKCA P17252 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14272622 0.75 TSHR (0.39) ESR1NAAATSHRTP53CYP3A4
SCHEMBL1534187 0.71 TSHR (0.36) ESR1NAAATSHRTP53CYP3A4
SCHEMBL6749851 0.70 ALDH1A1 (0.38) ESR1NAAATSHRTP53CYP3A4
SCHEMBL4230578 0.69 ALDH1A1 (0.37) ESR1NAAATSHRTP53CYP3A4
SCHEMBL818550 0.67 TSHR (0.50) ESR1TSHRTP53CYP3A4MAPK1
SCHEMBL4192255 0.66 NAAA (0.40) ESR1NAAATSHRTP53CYP3A4
SCHEMBL818740 0.66 ALDH1A1 (0.51) ESR1TSHRTP53CYP3A4MAPK1
SCHEMBL16086360 0.66 NAAA (0.50) NAAATSHRTP53CYP3A4MAPK1
SCHEMBL17048755 0.65 NAAA (0.46) NAAATSHRTP53CYP3A4MAPK1
SCHEMBL14967650 0.65 TSHR (0.46) NAAATSHRTP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008126971-A1 POLYMER NANO PARTICLE CONTAINING UV BLOCKING MATERIAL AND METHOD FOR PREPARING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-10-23 WO claimed
CN-116725903-A Cosmetic base, cosmetic comprising same, and water-in-oil type sunscreen cosmetic 日油株式会社 2023-09-12 CN disclosed
WO-2008126971-A1 POLYMER NANO PARTICLE CONTAINING UV BLOCKING MATERIAL AND METHOD FOR PREPARING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-10-23 WO disclosed
EP-0887070-B1 External composition for skin comprising sphingoglycolipid KIBUN FOOD CHEMIFA (JP) 2004-12-22 EP disclosed
US-6514744-B2 Skin moisturizer KIBUN FOOD CHEMIFA CO., LTD. (JP) 2003-02-04 US disclosed
US-20020164351-A1 External compositions for skin comprising sphingoglycolipid KIBUN FOOD CHEMIFA CO., LTD. (JP) 2002-11-07 US disclosed
US-6348201-B2 SPHINGOGLYCOLIPID AVAILABLE AS COSMETIC AND MEDICINE, HAS POTENT MOISTURIZING EFFEACT AND PREVENTIVE EFFECT AGAINST SKIN ROUGHNESS; SPHINOGGLYCOLIPID CONTAINING SUGAR MOITIES AND AMIDE GROUP KIBUN FOOD CHEMIFA CO., LTD. (JP) 2002-02-19 US disclosed
US-20020006414-A1 EXTERNAL COMPOSITION FOR SKIN COMPRISING SPHINGOGLYCOLIPID FOODCHEMIFA CO., LTD. (JP) 2002-01-17 US disclosed
EP-0887070-A1 External composition for skin comprising sphingoglycolipid Kibun Food ChemiFA Co., Ltd. (JP) 1998-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020164351-A1 External compositions for skin comprising sphingoglycolipid UGCG, UGGT1, MAN1B1 ESR1 4778/4885NAAA 723/4885TSHR 4080/4885
US-20020006414-A1 EXTERNAL COMPOSITION FOR SKIN COMPRISING SPHINGOGLYCOLIPID UGCG, MAN2A1, GALK1 ESR1 4718/4885NAAA 541/4885TSHR 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.