Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255554 | 0.84 | NPC1 (0.48) | NPC1POLBRAB9ACYP4F2CYP4A11 | |
| SCHEMBL17422637 | 0.83 | CSNK2A1 (0.41) | ALDH1A1TSHRCA2 | |
| SCHEMBL17151923 | 0.83 | CA2 (0.32) | CYP4F2CYP4A11TRPV1ALDH1A1CA2 | |
| SCHEMBL16959158 | 0.82 | HTT (0.47) | NPC1POLBRAB9ACYP4F2CYP4A11 | |
| SCHEMBL6765922 | 0.82 | CA2 (0.45) | NPC1POLBRAB9ACYP4F2CYP4A11 | |
| SCHEMBL4217006 | 0.81 | CSNK2A1 (0.42) | NPC1POLBRAB9ACYP4F2CYP4A11 | |
| SCHEMBL6301878 | 0.81 | POLB (0.56) | NPC1POLBRAB9AFYNHTT | |
| SCHEMBL334082 | 0.81 | SLC22A12 (0.40) | NPC1POLBRAB9ACYP4F2CYP4A11 | |
| SCHEMBL23673569 | 0.79 | SLC6A4 (0.42) | NPC1POLBRAB9ACYP4F2CYP4A11 | |
| SCHEMBL29887121 | 0.79 | SLC6A4 (0.42) | NPC1POLBRAB9ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166644-B1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD (GB) | 2019-06-19 | — | — | EP | disclosed |
| US-20170196990-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD. (GB) | 2017-07-13 | — | — | US | disclosed |
| US-20170196990-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD. (GB) | 2017-07-13 | — | — | US | disclosed |
| US-20170196990-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD. (GB) | 2017-07-13 | — | — | US | disclosed |
| EP-3166644-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | Adc Biotechnology Ltd (GB) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005744-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD (GB) | 2016-01-14 | — | — | WO | disclosed |
| WO-2016005744-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD (GB) | 2016-01-14 | — | — | WO | disclosed |
| WO-2015152128-A1 | AMINO ACID PRECURSOR, AMINO ACID, AND PRODUCTION METHOD FOR AMINO ACID, AND PET DIAGNOSTIC TRACER USING AMINO ACID | 長瀬産業株式会社 | 2015-10-08 | — | — | WO | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| CN-101119747-A | Tissue factor production inhibitor | SANKYO CO (JP) | 2008-02-06 | — | — | CN | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | NPC1 747/4885POLB 2926/4885RAB9A 3919/4885 |
| US-20170196990-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | SBDS, ADCY8, DCK | NPC1 4777/4885POLB 569/4885RAB9A 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.