Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359455 | 0.93 | MAPT (0.52) | MAPTALDH1A1PTGS1TDP1L3MBTL1 | |
| SCHEMBL8251886 | 0.78 | TDP1 (0.47) | MAPTALDH1A1TDP1L3MBTL1CES2 | |
| SCHEMBL3349906 | 0.77 | TDP1 (0.45) | MAPTALDH1A1PTGS1TDP1L3MBTL1 | |
| SCHEMBL5497904 | 0.74 | LMNA (0.46) | MAPTALDH1A1TDP1L3MBTL1CES2 | |
| SCHEMBL4751891 | 0.72 | ANPEP (0.44) | PTGS1TDP1L3MBTL1CES2CES1 | |
| Phenylglyoxal SCHEMBL5493637 | 0.71 | ALDH1A1 (0.56) | MAPTALDH1A1PTGS1TDP1L3MBTL1 | |
| SCHEMBL5495906 | 0.70 | MDM2 (0.43) | MAPTALDH1A1PTGS1TDP1L3MBTL1 | |
| SCHEMBL3345719 | 0.69 | CES1 (0.43) | MAPTALDH1A1TDP1L3MBTL1CES2 | |
| SCHEMBL3345510 | 0.68 | CES1 (0.45) | MAPTALDH1A1TDP1L3MBTL1CES2 | |
| SCHEMBL3349186 | 0.68 | TDP1 (0.44) | MAPTALDH1A1TDP1L3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080071062-A1 | TETRA-, PENTA-, HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | HAVIV FORTUNA | 2008-03-20 | — | — | US | disclosed |
| US-7169888-B2 | Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2007-01-30 | — | — | US | disclosed |