Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 3/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051559 | 0.81 | PGK1 (0.39) | HMGCRPGK1PGK2 | |
| SCHEMBL5052075 | 0.79 | FDPS (0.36) | HMGCRPGK1PGK2FDPS | |
| SCHEMBL4609991 | 0.79 | KDM4E (0.40) | KDM4EGAASMN1; SMN2POLBKMT2A | |
| SCHEMBL5010542 | 0.75 | PGK1 (0.53) | GAAKMT2APGK1PGK2ALDH1A1 | |
| SCHEMBL4133796 | 0.73 | PGK1 (0.36) | PGK1PGK2ALDH1A1 | |
| SCHEMBL2164428 | 0.72 | CA1 (0.44) | KDM4EGAASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4538998 | 0.71 | CES2 (0.41) | GAAPGK1PGK2 | |
| SCHEMBL2033234 | 0.71 | TSHR (0.31) | — | |
| SCHEMBL11761874 | 0.69 | PTPN1 (0.36) | PGK1PGK2FDPS | |
| SCHEMBL2032077 | 0.68 | TXNRD1 (0.39) | SMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030072-A1 | COMPOUND FOR INHIBITING THE FORMATION OF BETA-AMYLOID FIBRIL, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-03-13 | — | — | WO | disclosed |