SCHEMBL505952

SCHEMBL505952

Cc1ccc(N)c(C(C)O)c1C(C)O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.34
CYP3A4 P08684 5/20 0.34
ALDH1A1 P00352 3/20 0.34
TSHR P16473 3/20 0.34
CASP1 P29466 2/20 0.34
MAPT P10636 1/20 0.33
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPA1 O75762 1/20 0.30
PTGS1 P23219 1/20 0.30
CACNA1C Q13936 1/20 0.30
POLB P06746 1/20 0.30
CD44 P16070 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037027 0.88 ALDH1A1 (0.34) TDP1CYP3A4ALDH1A1TSHRTP53
SCHEMBL3875795 0.84 CYP3A4 (0.33) TDP1CYP3A4ALDH1A1TSHRCASP1
SCHEMBL8973695 0.80 CD44 (0.48) TDP1CYP3A4ALDH1A1TSHRTRPA1
SCHEMBL7571572 0.79 HIF1A (0.32) ALDH1A1
SCHEMBL1532606 0.76 CYP3A4 (0.37) TDP1CYP3A4ALDH1A1TSHRCASP1
SCHEMBL6397577 0.74 TRPA1 (0.40) TDP1CYP3A4ALDH1A1TSHRCASP1
SCHEMBL6122863 0.74 CYP3A4 (0.31) CYP3A4TSHR
SCHEMBL688608 0.74 TSHR (0.46) TDP1CYP3A4ALDH1A1TSHRMAPT
SCHEMBL4852014 0.73 CYP3A4 (0.43) TDP1CYP3A4ALDH1A1TSHRCASP1
SCHEMBL5830708 0.72 LMNA (0.38) TDP1CYP3A4ALDH1A1TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3700465-B1 ENDOLUMINAL DEVICE AND POLYMER ENDOLOGIX LLC (US) 2025-07-16 EP claimed
US-12240973-B2 Endoluminal device and polymer ENDOLOGIX LLC (US) 2025-03-04 US claimed
US-20200324018-A1 ENDOLUMINAL DEVICE AND POLYMER SILICON VALLEY BANK 2020-10-15 US claimed
EP-3700465-A1 ENDOLUMINAL DEVICE AND POLYMER Endologix, Inc. (US) 2020-09-02 EP claimed
WO-2018071920-A1 CURABLE URETHANE DIMETHACRYLATES AND DENTAL RESTORATIVE COMPOSITIONS THEREOF DM HEALTHCARE PRODUCTS, INC (US) 2018-04-19 WO claimed
US-9523029-B2 Two-component mortar composition and its use HILTI AKTIENGESELLSCHAFT (LI) 2016-12-20 US claimed
EP-2640675-B1 TWO-COMPONENT MORTAR COMPOSITION AND ITS USE HILTI AG (LI) 2015-09-09 EP claimed
EP-2640675-A1 TWO-COMPONENT MORTAR COMPOSITION AND ITS USE HILTI Aktiengesellschaft (LI) 2013-09-25 EP claimed
US-20130237634-A1 Two-Component Mortar Composition and its Use HILTI AKTIENGESELLSCHAFT (LI) 2013-09-12 US claimed
US-20130213549-A1 ADHESIVE AND METHOD FOR BINDING ARTIFICIAL PLASTIC TEETH DENTSPLY INTERNATIONAL INC. (US) 2013-08-22 US claimed
WO-2009110848-A1 LOW SHRINKAGE MULTIFUNCTIONAL SSQ RESINS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-09-11 WO claimed
JP-2009522001-A 2009-06-11 JP claimed
EP-1973513-A2 LIGHT-CURABLE BONE GROWTH MATERIAL FOR TREATING DENTAL BONE DEFECTS DENTSPLY INTERNATIONAL, INC. (US) 2008-10-01 EP claimed
US-20080230167-A1 Adhesive and method for binding artificial plastic teeth DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) 2008-09-25 US claimed
EP-1924235-A2 ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH DENTSPLY INTERNATIONAL, INC. (US) 2008-05-28 EP claimed
US-20080041520-A1 Adhesive and method for binding artificial plastic teeth DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) 2008-02-21 US claimed
US-20070269518-A1 Light-curable bone growth material for treating dental bone defects WALLINE KATHERINE S 2007-11-22 US claimed
WO-2007079053-A2 LIGHT-CURABLE BONE GROWTH MATERIAL FOR TREATING DENTAL BONE DEFECTS DENTSPLY INTERNATIONAL INC. (US) 2007-07-12 WO claimed
WO-2007022503-A2 ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH DENTSPLY INTERNATIONAL INC. (US) 2007-02-22 WO claimed
US-4107845-A SELF-CURING, INORGANIC FIBER FILLER, ACRYLATE POLYMER, PEROXIDE CATALYST LEE PHARMACEUTICALS (US) 1978-08-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130213549-A1 ADHESIVE AND METHOD FOR BINDING ARTIFICIAL PLASTIC TEETH MECP2, HDAC10, DNMT1 TDP1 3358/4885CYP3A4 4671/4885ALDH1A1 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.