Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037027 | 0.90 | ALDH1A1 (0.34) | HIF1AADRA2AADRA2CLMNAKDM4E | |
| SCHEMBL505952 | 0.79 | TDP1 (0.34) | ALDH1A1 | |
| SCHEMBL4852014 | 0.75 | CYP3A4 (0.43) | HIF1AADRA2AADRA2CLMNAKDM4E | |
| SCHEMBL7089983 | 0.73 | PDE2A (0.32) | — | |
| SCHEMBL3875795 | 0.73 | CYP3A4 (0.33) | ALDH1A1 | |
| SCHEMBL7577626 | 0.73 | — | — | |
| SCHEMBL6865176 | 0.71 | CYP1A2 (0.32) | ADRB2 | |
| SCHEMBL30937674 | 0.71 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL11415039 | 0.71 | GCGR (0.33) | ALDH1A1GAA | |
| SCHEMBL6122863 | 0.71 | CYP3A4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, CYP1B1, ALDH7A1 | HIF1A 1719/4885ADRA2A 2412/4885ADRA2C 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.