SCHEMBL505983

SCHEMBL505983

O=Cc1ccc(CCl)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
CYP2A6 P11509 4/20 0.46
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
ALDH1A1 P00352 7/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
ALDH1A3 P47895 2/20 0.43
ALDH3A1 P30838 1/20 0.43
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TYR P14679 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP2A13 Q16696 1/20 0.41
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL6158111 0.83 ALDH1A1 (0.64) HSD17B10CYP2A6ALDH1A1LMNARAB9A
SCHEMBL1299394 0.82 RAB9A (0.59) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
(Chloromethyl)Benzene SCHEMBL27895882 0.81 ALDH1A1 (0.61) HSD17B10CYP2A6ALDH1A1LMNARAB9A
SCHEMBL3976211 0.80 CYP2A6 (0.52) HSD17B10CYP2A6ALDH5A1ABATALDH1A1
SCHEMBL4024088 0.80 HSD17B10 (0.48) HSD17B10CYP2A6ALDH5A1ABATALDH1A1
SCHEMBL5429778 0.78 CYP2A6 (0.50) HSD17B10CYP2A6ALDH5A1ABATALDH1A1
SCHEMBL11835184 0.78 CA1 (0.41) CA1CA2HPGD
SCHEMBL11835189 0.78 CA1 (0.41) CA1CA2HPGD
SCHEMBL3012913 0.77 ALDH1A1 (0.46) HSD17B10CYP2A6ALDH5A1ABATALDH1A1
SCHEMBL97582 0.76 CA1 (0.52) ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4467143-B1 METHOD FOR PREPARING 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE CELGENE CORP (US) 2026-03-11 EP claimed
CN-120078769-A Composition containing pyruvate and preparation method and application thereof 江苏长泰药业股份有限公司 2025-06-03 CN claimed
CN-119456043-A Preparation method and application of Cu-MOF carrier supported Ru catalyst 厦门大学 2025-02-18 CN claimed
CN-119371629-A An aqueous dispersant Water-based color paste and preparation method thereof 中山凯普助剂有限公司 2025-01-28 CN claimed
CN-119372490-A Method for separating vanadium and tungsten from waste SCR denitration catalyst leaching liquid through ion exchange resin 安徽思凯瑞环保科技有限公司 2025-01-28 CN claimed
CN-119119512-A Preparation method of hydrogel composite material for soil heavy metal adsorption 江西省农业科学院农产品质量安全与标准研究所(江西省绿色农业研究中心) 2024-12-13 CN claimed
US-20240409727-A1 Functional modification of reclaimed rubber materials and use thereof in making safety gloves ZHEJIANG KANGLONGDA SPECIAL PROTECTION TECHNOLOGY CO., LTD. (CN) 2024-12-12 US claimed
EP-4467143-A2 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND Celgene Corporation (US) 2024-11-27 EP claimed
WO-2024067890-A1 FUNCTIONAL MODIFICATION OF RECYCLED RUBBER MATERIAL AND APPLICATION THEREOF IN SAFETY GLOVES 浙江康隆达特种防护科技股份有限公司 2024-04-04 WO claimed
CN-117603127-A Novel chalcone derivative containing nitrogen heterocycle, and preparation method and application thereof 新疆医科大学 2024-02-27 CN claimed
CN-103664810-A Process for synthesizing letrozole BANNERBIO NUTRACEUTICALS INC 2014-03-26 CN claimed
CN-102863383-A Preparation method of oxygen bleaching activator tribasic copper chloride (TBCC) UNIV EAST CHINA SCIENCE & TECH 2013-01-09 CN claimed
EP-1833815-B1 A PROCESS FOR PREPARATION OF IMATINIB BASE INST FARMACEUTYCZNY (PL) 2010-09-15 EP claimed
EP-1143970-B1 PYRIDINE COMPOUNDS, USE AND PREPARATION THEREOF SOUTHERN RES INST (US) 2010-07-21 EP claimed
US-6949678-B2 Oxime ester photoinitiators CIBA SPECIALTY CHEMICALS CORP. (US) 2005-09-27 US claimed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US claimed
EP-0594540-B1 Antiretroviral acyl compounds CIBA GEIGY AG (CH) 1998-04-01 EP claimed
EP-0594540-A1 Antiretroviral acyl compounds CIBA-GEIGY AG (CH) 1994-04-27 EP claimed
US-4868241-A POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE AMERICAN CYANAMID COMPANY (US) 1989-09-19 US claimed
EP-0231922-A2 Electron beam and X-ray resists AMERICAN CYANAMID COMPANY (US) 1987-08-12 EP claimed