Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108991 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL2097664 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL10931231 | 0.82 | SRD5A2 (0.50) | ALDH1A1PARP10FFAR1 | |
| SCHEMBL514175 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL8213432 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL19328352 | 0.81 | KMT2A (0.47) | ALDH1A1GSK3BCES2CES1MEN1 | |
| SCHEMBL1258169 | 0.80 | HPGD (0.54) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL4932919 | 0.80 | SLC6A2 (0.57) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL25545681 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CA1CA2GSK3B | |
| SCHEMBL1303238 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CA1CA2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-09-25 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | 7TM PHARMA A/S (DK) | 2008-05-22 | — | — | US | disclosed |
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | 7TM PHARMA A/S (DK) | 2008-05-22 | — | — | US | disclosed |
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | 7TM PHARMA A/S (DK) | 2008-05-22 | — | — | US | disclosed |
| EP-1758874-A1 | SUBSTITUTED THIAZOLEACETIC ACIDS AS CRTH2 LIGANDS | 7TM Pharma A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005116001-A1 | SUBSTITUTED THIAZOLEACETIC AS CRTH2 LIGANDS | 7TM PHARMA A/S (DK) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | UGDH, GALE, UGGT1 | ALDH1A1 726/4885CYP1A2 2763/4885CA1 4286/4885 |
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | UGDH, GALE, UGGT1 | ALDH1A1 726/4885CYP1A2 2763/4885CA1 4286/4885 |
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | HRH1, HRH2, HRH3 | ALDH1A1 832/4885CYP1A2 1022/4885CA1 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.