Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12602855 | 0.85 | GSK3B (0.46) | KMT2AALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL19328379 | 0.83 | CES2 (0.45) | KMT2AGSK3BCES2CES1MEN1 | |
| SCHEMBL5054802 | 0.82 | ALKBH5 (0.47) | KMT2AALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL5052427 | 0.81 | MMP2 (0.47) | KMT2AALDH1A1GSK3BCES2CES1 | |
| SCHEMBL5055106 | 0.81 | CYP2C9 (0.51) | KMT2AALDH1A1GSK3BLMNACES2 | |
| SCHEMBL3110619 | 0.81 | GSK3B (0.48) | KMT2AALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL12593806 | 0.81 | TDP1 (0.47) | KMT2AALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL5060223 | 0.81 | ALDH1A1 (0.61) | KMT2AALDH1A1GSK3BLMNACES2 | |
| SCHEMBL4894019 | 0.81 | GSK3B (0.42) | KMT2AALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL16922196 | 0.81 | GSK3B (0.42) | KMT2AALDH1A1SMN1; SMN2GSK3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383005-B | Preparation method of 6-methyl-2- (4-methylphenyl) imidazo [1,2-a ] pyridine-3-acetic acid | 华东理工大学 | 2020-03-13 | — | — | CN | claimed |
| CN-107383005-B | Preparation method of 6-methyl-2- (4-methylphenyl) imidazo [1,2-a ] pyridine-3-acetic acid | 华东理工大学 | 2020-03-13 | — | — | CN | disclosed |
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-09-25 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | UGDH, GALE, UGGT1 | KMT2A 652/4885ALDH1A1 726/4885SMN1; SMN2 3230/4885 |
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | UGDH, GALE, UGGT1 | KMT2A 652/4885ALDH1A1 726/4885SMN1; SMN2 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.