SCHEMBL5061152

SCHEMBL5061152

Oc1cc2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)CC3

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.34
▸ STAT1 P42224 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2673638 0.89 — —
SCHEMBL431893 0.89 STAT3 (0.40) STAT3STAT1
SCHEMBL28228962 0.88 STAT3 (0.39) STAT3STAT1
SCHEMBL28129220 0.88 STAT3 (0.39) STAT3STAT1
SCHEMBL28442368 0.88 STAT3 (0.39) STAT3STAT1
SCHEMBL27493312 0.88 STAT3 (0.39) STAT3STAT1
SCHEMBL31407862 0.88 STAT3 (0.39) STAT3STAT1
Benzene SCHEMBL28299122 0.86 STAT3 (0.44) STAT3STAT1
SCHEMBL3820256 0.86 STAT3 (0.35) STAT3STAT1
SCHEMBL25612 0.86 STAT3 (0.35) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330500-A A kind of Stereoselective synthesizing process of 6 beta-hydroxy -7,8- dihydro-morphine derivatives 宜昌人福药业有限责任公司 2019-10-15 — — CN claimed
US-8968715-B2 Drug delivery systems for photodynamic therapy THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-03-03 — — US claimed
US-20070086973-A1 Drug delivery systems for photodynamic therapy THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2007-04-19 — — US claimed
US-20040152887-A1 Regioisomerically pure oxochlorins and methods of synthesis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-08-05 — — US claimed
US-6765092-B2 OXIDIZING A CHLORIN TO PRODUCE A MIXTURE OF HYDROXYCHLORIN AND OXOCHLORIN, AND THEN OXIDIZING THE HYDROXYCHLORIN, PREFERABLY WITH DDQ NORTH CAROLINA STATE UNIVERSITY 2004-07-20 — — US claimed
US-20040102430-A1 Drug delivery systems for photodynamic therapy CHOWDHARY RUBINAH K (CA) 2004-05-27 — — US claimed
US-6693093-B2 FOR PHOTOSENSITIZER DRUG RELEASE IN A FORM SUITABLE FOR ADMINISTRATION TO SUBJECTS UNDERGOING PHOTODYNAMIC THERAPY THE UNIVERSITY OF BRITISH COLUMBIA (UBC) (CA) 2004-02-17 — — US claimed
WO-2003050082-A2 REGIOISOMERICALLY PURE OXOCHLORINS AND METHODS OF SYNTHESIS NORTH CAROLINA STATE UNIVERSITY (US) 2003-06-19 — — WO claimed
US-20020155089-A1 Drug delivery systems for photodynamic therapy UNIVERSITY OF BRITISH COLUMBIA, THE (CA) 2002-10-24 — — US claimed
US-20020137925-A1 Regioisomerically pure oxochlorins and methods of synthesis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-09-26 — — US claimed
WO-2001085212-A2 DRUG DELIVERY SYSTEMS FOR PHOTODYNAMIC THERAPY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-11-15 — — WO claimed
US-5703230-A Meso-monoiodo-substituted tetramacrocyclic compounds and methods for making and using the same UNIVERSITY OF BRITISH COLUMBIA (CA) 1997-12-30 — — US claimed
EP-0794954-A1 MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME QUADRA LOGIC TECHNOLOGIES INC. (CA) 1997-09-17 — — EP claimed
WO-1996016966-A1 MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME QUADRA LOGIC TECHNOLOGIES, INC. (CA) 1996-06-06 — — WO claimed
CN-110330500-A A kind of Stereoselective synthesizing process of 6 beta-hydroxy -7,8- dihydro-morphine derivatives 宜昌人福药业有限责任公司 2019-10-15 — — CN disclosed
EP-2946795-B1 TISSUE ADHESIVE AND PROCESS FOR PRODUCING SAME NAT INST MATERIALS SCIENCE (JP) 2019-04-17 — — EP disclosed
US-10064973-B2 Tissue adhesive and method for producing same NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2018-09-04 — — US disclosed
EP-0794954-A1 MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME QUADRA LOGIC TECHNOLOGIES INC. (CA) 1997-09-17 — — EP disclosed
WO-1996016966-A1 MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME QUADRA LOGIC TECHNOLOGIES, INC. (CA) 1996-06-06 — — WO disclosed
WO-1996013504-A1 β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES UNIVERSITY OF BRITISH COLUMBIA (CA) 1996-05-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070086973-A1 Drug delivery systems for photodynamic therapy PIN1, PPOX, DHFR STAT3 2013/4885STAT1 3494/4885
US-20020155089-A1 Drug delivery systems for photodynamic therapy PIN1, PPOX, DHFR STAT3 2013/4885STAT1 3494/4885
US-20040152887-A1 Regioisomerically pure oxochlorins and methods of synthesis DDT, AOC1, DNMT1 STAT3 2540/4885STAT1 2081/4885
US-20020137925-A1 Regioisomerically pure oxochlorins and methods of synthesis DDT, AOC1, DNMT1 STAT3 2535/4885STAT1 1931/4885
US-20040102430-A1 Drug delivery systems for photodynamic therapy PIN1, PPOX, DHFR STAT3 2013/4885STAT1 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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