Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877422 | 0.92 | KLK7 (0.43) | KLK7KLK5MAPTCTSBCTSS | |
| SCHEMBL5063469 | 0.92 | CTSB (0.42) | KLK7KLK5MAPTCTSBCTSS | |
| SCHEMBL14497783 | 0.91 | MAPT (0.46) | KLK7KLK5MAPTCTSSITGB3 | |
| SCHEMBL5063416 | 0.89 | KLK7 (0.40) | KLK7KLK5MAPTCTSBCTSS | |
| SCHEMBL13479162 | 0.88 | KLK7 (0.44) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL13479151 | 0.87 | KLK7 (0.43) | KLK7KLK5MAPTCTSSCTSK | |
| SCHEMBL5058878 | 0.85 | PTGER4 (0.44) | CTSSCTSKITGB3 | |
| SCHEMBL13479127 | 0.85 | CTSS (0.49) | KLK7MAPTCTSBCTSSCTSK | |
| SCHEMBL14534407 | 0.85 | PTGER4 (0.48) | KLK7KLK5MAPTCTSBCTSS | |
| SCHEMBL4880594 | 0.84 | PTGER4 (0.48) | KLK7KLK5MAPTCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AICURIS GMBH & CO. KG (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AADAC, AAAS, NOD2 | KLK7 2611/4885KLK5 3035/4885MAPT 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.