Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063456 | 0.92 | KLK7 (0.41) | CTSBCTSSCTSKKLK7KLK5 | |
| SCHEMBL13479127 | 0.91 | CTSS (0.49) | CTSBCTSSCTSKSYKTACR1 | |
| SCHEMBL4889692 | 0.90 | CTSB (0.47) | CTSBCTSSCTSKSYKTACR1 | |
| SCHEMBL1023687 | 0.90 | TACR1 (0.47) | CTSBCTSSCTSKSYKTACR1 | |
| SCHEMBL4847576 | 0.90 | TACR1 (0.47) | CTSBCTSSCTSKSYKTACR1 | |
| SCHEMBL14497714 | 0.86 | CTSS (0.45) | CTSBCTSSCTSKSYKTACR1 | |
| Hydrochloric Acid SCHEMBL5063426 | 0.86 | ITGB3 (0.39) | CTSBCTSSCTSKITGB3ITGAV | |
| SCHEMBL13479128 | 0.86 | TACR1 (0.46) | CTSBCTSSCTSKSYKTACR1 | |
| SCHEMBL14497710 | 0.86 | CTSS (0.46) | CTSBCTSSCTSKTACR1MAPT | |
| SCHEMBL13479135 | 0.86 | TACR1 (0.43) | CTSBCTSSCTSKSYKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AICURIS GMBH & CO. KG (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AADAC, AAAS, NOD2 | CTSB 60/4885CTSS 88/4885CTSK 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.