Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260648 | 0.86 | MTNR1A (0.53) | MTNR1AKDM4ELMNA | |
| SCHEMBL1145761 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH | |
| SCHEMBL6262492 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH | |
| SCHEMBL300072 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH | |
| SCHEMBL506237 | 0.79 | EED (0.46) | EEDABCG2KDM4CFAAHL3MBTL1 | |
| SCHEMBL25477727 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH | |
| SCHEMBL700738 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH | |
| SCHEMBL2168952 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH | |
| SCHEMBL2602430 | 0.79 | EED (0.46) | EEDABCG2KDM4CFAAHMTNR1A | |
| SCHEMBL1145758 | 0.79 | EED (0.46) | EEDABCG2KDM4CP2RX7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288933-B1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUND FOR RES DEV (US) | 2021-10-06 | — | — | EP | disclosed |
| EP-3288933-B1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUND FOR RES DEV (US) | 2021-10-06 | — | — | EP | disclosed |
| US-10370328-B2 | Oxindole compounds and pharmaceutical compositions thereof | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2019-08-06 | — | — | US | disclosed |
| US-10370328-B2 | Oxindole compounds and pharmaceutical compositions thereof | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180134659-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2018-05-17 | — | — | US | disclosed |
| US-20180134659-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2018-05-17 | — | — | US | disclosed |
| US-20180134659-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2018-05-17 | — | — | US | disclosed |
| WO-2016176420-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2016-11-03 | — | — | WO | disclosed |
| EP-1720836-B1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2014-04-16 | — | — | EP | disclosed |
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20040209875-A1 | Nonsteroidal antiinflammatory agents | SCHERIN AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | US | disclosed |
| WO-2004058733-A1 | NON-STEROIDAL ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-07-15 | — | — | WO | disclosed |
| US-5731321-A | Endothelin receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5700807-A | Endothelin receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-23 | — | — | US | disclosed |
| CN-1155539-A | Endothelin receptor antagonists | MERCK PATENT GMBH (DE) | 1997-07-30 | — | — | CN | disclosed |
| EP-0757039-A1 | Endothelin receptor antagonists | MERCK PATENT GmbH (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0755934-A1 | Endothelin receptor antagonists | MERCK PATENT GmbH (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0215492-B1 | USE OF PERFLUOROPOLYETHER DERIVATIVES FOR PROTECTING BUILDING MATERIALS FROM ATMOSPHERICAL AGENTS | AUSIMONT S.p.A. (IT) | 1991-05-08 | — | — | EP | disclosed |
| US-4746550-A | Use of perfluoropolyether derivatives for protecting stone materials from atmospheric agents | AUSIMONT S.P.A. (IT) | 1988-05-24 | — | — | US | disclosed |
| EP-0215492-A2 | Use of perfluoropolyether derivatives for protecting building materials from atmospherical agents | AUSIMONT S.p.A. (IT) | 1987-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370328-B2 | Oxindole compounds and pharmaceutical compositions thereof | PARK7, OPRK1, COMT | EED 2904/4885ABCG2 77/4885KDM4C 3202/4885 |
| US-20180134659-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PARK7, OPRK1, COMT | EED 2904/4885ABCG2 77/4885KDM4C 3202/4885 |
| US-20040209875-A1 | Nonsteroidal antiinflammatory agents | PTGS1, PTGER1, PTGES | EED 4217/4885ABCG2 2419/4885KDM4C 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.