Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729312 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPK1HTTGAAUSP2 | |
| SCHEMBL5064083 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPK1HTTGAAUSP2 | |
| SCHEMBL1779323 | 0.83 | L3MBTL1 (0.57) | SMN1; SMN2MAPK1HTTGAAUSP2 | |
| SCHEMBL2809845 | 0.74 | HTT (0.42) | SMN1; SMN2MAPK1HTTGAAKDM4E | |
| SCHEMBL14553828 | 0.72 | ALDH1A1 (0.69) | MAPK1GAAUSP2KDM4EALDH1A1 | |
| SCHEMBL3346074 | 0.71 | MEN1 (0.35) | KMT2AMEN1 | |
| SCHEMBL7901133 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1HTTGAAKDM4E | |
| SCHEMBL727848 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1HTTGAAKDM4E | |
| SCHEMBL727417 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1HTTGAAKDM4E | |
| SCHEMBL727667 | 0.68 | NOS1 (0.44) | SMN1; SMN2MAPK1HTTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979334-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong Wha Pharmaceutical. Ind. Co., Ltd. (KR) | 2008-10-15 | — | — | EP | claimed |
| WO-2007089101-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG WHA PHARMACEUTICAL IND.CO., LTD. (KR) | 2007-08-09 | — | — | WO | claimed |