SCHEMBL5064665

SCHEMBL5064665

[CH]1C=CCc2cc(-c3ccccc3)ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.37
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
SRD5A1 P18405 1/20 0.35
ALOX5 P09917 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
KDM1A O60341 4/20 0.35
KDM1B Q8NB78 1/20 0.35
TYRO3 Q06418 1/20 0.34
NTRK2 Q16620 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
DYRK1B Q9Y463 1/20 0.34
HSD17B3 P37058 1/20 0.34
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5064122 0.85 TYRO3 (0.38) TDP2PARP10PARP11SRD5A1ALOX5
SCHEMBL4126787 0.81 TDP2 (0.39) TDP2PARP10PARP11ALOX5KDM4E
SCHEMBL183111 0.73 CA1 (0.42) MAOB
SCHEMBL21120521 0.71 DRD2 (0.35) TDP2PARP10PARP11SRD5A1ALOX5
SCHEMBL3861910 0.71 DRD2 (0.36) KDM4EMEN1GAAMAPTKMT2A
SCHEMBL7782887 0.71 PNMT (0.34) TDP2PARP10PARP11SRD5A1KDM1A
SCHEMBL290039 0.71 MEN1 (0.38) KDM4EMEN1MAPTKMT2ANPC1
SCHEMBL3839016 0.71
SCHEMBL5158791 0.69 TYRO3 (0.40) TDP2PARP10PARP11ALOX5KDM4E
SCHEMBL5076746 0.68 ALOX5 (0.40) ALOX5KDM4EMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1882694-A1 THIOPHENE COMPOUND HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2008-01-30 EP disclosed