Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 8/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064754 | 0.90 | CNR1 (0.56) | PLECALDH1A1CNR1RARARARB | |
| SCHEMBL5054116 | 0.89 | CNR1 (0.55) | PLECALDH1A1CNR1RARARARB | |
| SCHEMBL5064844 | 0.87 | PLEC (0.67) | PLECALDH1A1CNR1RARARARB | |
| SCHEMBL5057174 | 0.82 | ALDH1A1 (0.55) | PLECALDH1A1CNR1RECQLSIRT5 | |
| SCHEMBL13808030 | 0.78 | CNR1 (0.65) | PLECCNR1CNR2POLBSMN1; SMN2 | |
| SCHEMBL5057185 | 0.77 | CNR1 (0.77) | ALDH1A1CNR1CNR2POLBSMN1; SMN2 | |
| SCHEMBL5577088 | 0.75 | CNR1 (0.59) | CNR1CNR2SMN1; SMN2TP53 | |
| SCHEMBL5057655 | 0.74 | DRD2 (0.54) | PLECALDH1A1CNR1RECQLSIRT5 | |
| SCHEMBL5064756 | 0.74 | CNR1 (0.56) | PLECALDH1A1CNR1RECQLSIRT5 | |
| SCHEMBL5057733 | 0.74 | CNR1 (0.83) | ALDH1A1CNR1CNR2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090805-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090805-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | CNR1, CNR2, FAAH | PLEC 2850/4885ALDH1A1 888/4885CNR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.