Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463518 | 0.75 | CSNK1A1 (0.61) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| SCHEMBL11882940 | 0.74 | CA1 (0.38) | CA12CA1CA2CA9CA7 | |
| SCHEMBL5064901 | 0.72 | DHFR (0.50) | ADORA1ADORA2ACSNK1A1CLK4CA12 | |
| SCHEMBL2473930 | 0.72 | DHFR (0.58) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| SCHEMBL27612323 | 0.71 | CSNK1A1 (0.55) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| Hydrochloric Acid SCHEMBL15487768 | 0.71 | DHFR (0.56) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| SCHEMBL28447630 | 0.70 | CSNK1A1 (0.50) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| Ampyrimine SCHEMBL1230765 | 0.69 | DHFR (0.61) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| SCHEMBL27716588 | 0.69 | CSNK1A1 (0.53) | ADORA1ADORA2ACSNK1A1CLK4DHFR | |
| SCHEMBL544518 | 0.69 | CA1 (0.49) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079907-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | claimed |