Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402554 | 0.87 | FFAR1 (0.58) | ALDH1A1LMNANPC1EPHX2RAB9A | |
| SCHEMBL506525 | 0.85 | AKR1C3 (0.49) | ALDH1A1LMNAHSD17B10MAPTNPC1 | |
| SCHEMBL15945485 | 0.81 | L3MBTL1 (0.51) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL10585564 | 0.81 | ALOX15 (0.44) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL8494650 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL9632889 | 0.80 | ATM (0.47) | ALDH1A1LMNAALOX15MAPK1MAPT | |
| SCHEMBL9632901 | 0.80 | ATM (0.47) | ALDH1A1LMNAALOX15MAPK1MAPT | |
| SCHEMBL28915433 | 0.79 | NPC1 (0.46) | ALDH1A1LMNAMAPTMEN1NPC1 | |
| SCHEMBL8148677 | 0.79 | ESR1 (0.52) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL3997211 | 0.79 | KIF11 (0.47) | ALDH1A1LMNAALOX15APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120304-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins and intermediates thereof, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-10-03 | — | — | EP | disclosed |