SCHEMBL5065402

SCHEMBL5065402

CC1(C)CC(N(C=O)CCCCCCN(C=O)C2CC(C)(C)N(OCc3ccc(Cl)cc3)C(C)(C)C2)CC(C)(C)N1OCc1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH4 P08319 1/20 0.35
KCNH2 Q12809 2/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 1/20 0.33
KCNA5 P22460 1/20 0.32
FPR3 P25089 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12301407 0.89
SCHEMBL10117348 0.88 ALDH1A1 (0.38) ADH1CADH1AADH4MEN1KMT2A
SCHEMBL5061910 0.88 ADH1C (0.35) ADH1CADH1AADH4KCNA5FPR3
SCHEMBL14706538 0.83 MEN1 (0.32) ADH1CADH1AADH4MEN1KMT2A
SCHEMBL10098235 0.79 ALDH1A1 (0.36) ADH1CADH1AADH4ALDH1A1
SCHEMBL6721413 0.75 ADH1A (0.49) ADH1CADH1AADH4
SCHEMBL5065428 0.73 IDO1 (0.41) MEN1KMT2AMAPTKCNA5L3MBTL1
SCHEMBL13508246 0.70 ADH1A (0.50) ADH1CADH1AADH4
SCHEMBL1276729 0.70 ADH1A (0.50) ADH1CADH1AADH4
SCHEMBL757255 0.69 ADH1A (0.49) ADH1CADH1AADH4L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377192-B2 Stabilisers for inanimate organic materials BASF SE (DE) 2013-02-19 US disclosed
EP-2450400-A2 Stabilisers for inanimate organic materials BASF SE (DE) 2012-05-09 EP disclosed
EP-2318454-B1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2012-02-29 EP disclosed
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2011-09-08 US disclosed
WO-2010023115-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2010-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS C1S, C1R, F12 ADH1C 655/4885ADH1A 1286/4885ADH4 2658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.