SCHEMBL5065428

SCHEMBL5065428

CC1(C)CC(N)CC(C)(C)N1OCc1ccc(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
AGXT P21549 2/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
KCNA5 P22460 1/20 0.36
CCR5 P51681 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2A P28223 1/20 0.35
SLC6A4 P31645 1/20 0.35
HRH1 P35367 1/20 0.35
HTR2B P41595 1/20 0.35
CHRNA4 P43681 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MAOB P27338 4/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5067477 0.84 ALDH1A1 (0.45) IDO1AGXTKDM1A
SCHEMBL3136334 0.78 AMPD2 (0.39) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL5065402 0.73 ADH1C (0.35) MEN1KMT2AMAPTCARM1PRMT6
SCHEMBL5065424 0.73 GAA (0.44) KMT2AGAAL3MBTL1
SCHEMBL6818225 0.71 AGXT (0.38) AGXTKMT2AMAOBGAA
SCHEMBL12517728 0.69
SCHEMBL9440082 0.68 CARM1 (0.46) KMT2ACARM1PRMT6
SCHEMBL17351108 0.68 ALDH1A1 (0.44) KMT2ACARM1PRMT6
SCHEMBL9042331 0.66
SCHEMBL2025192 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377192-B2 Stabilisers for inanimate organic materials BASF SE (DE) 2013-02-19 US disclosed
US-8377192-B2 Stabilisers for inanimate organic materials BASF SE (DE) 2013-02-19 US disclosed
EP-2450400-A2 Stabilisers for inanimate organic materials BASF SE (DE) 2012-05-09 EP disclosed
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2011-09-08 US disclosed
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2011-09-08 US disclosed
WO-2010023115-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2010-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS C1S, C1R, F12 IDO1 37/4885AGXT 2984/4885MEN1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.