SCHEMBL76000

SCHEMBL76000

Cl[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
TDP1 Q9NUW8 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
LMNA P02545 2/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29120692 1.00 TSHR (0.39) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL705847 0.97 ESR1 (0.40) TSHRTDP1ALDH1A1HSD17B10ESR1
Fluoride SCHEMBL5604818 0.97 TSHR (0.37) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL9586411 0.91 TSHR (0.33) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL28518241 0.91 TSHR (0.33) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL23000908 0.86 CYP1A2 (0.48) TDP1ALDH1A1HSD17B10ESR2LMNA
SCHEMBL5065485 0.86 ESR1 (0.34) TSHRESR1ESR2LMNAALOX12
SCHEMBL20829729 0.86 TSHR (0.50) TSHRESR1ESR2LMNANPC1
SCHEMBL6046614 0.86 ALDH1A1 (0.30) TSHRTDP1ALDH1A1ESR1ESR2
Toluene SCHEMBL28546934 0.86 ACHE (0.58) TSHRTDP1ALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11491 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121064369-B Stabilizer composition and preparation method thereof China Petroleum (Shanghai) New Materials Research Institute Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122080414-A Silicon carbide fiber precursor polycarbosilane and preparation method thereof 2026-05-26 CN claimed
CN-122060375-A Corrosion-resistant fireproof explosion-proof material, preparation method thereof and application thereof in electric power tunnel 南昌泰事达电气科技有限公司 2026-05-19 CN claimed
CN-119735819-B Flavonol hyperbranched flame retardant as well as preparation method and application thereof 桂林理工大学 2026-05-15 CN claimed
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
US-12479864-B2 Methods for preparing catalyst precursor materials DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-25 US claimed
CN-120157944-A Modified methyl silicone resin and preparation method thereof 山东东湖新材料有限公司 2025-06-17 CN claimed
CN-120138424-A High-performance beryllium copper alloy and preparation method thereof 广西太洋科技有限公司 2025-06-13 CN claimed
CN-120137449-A UV (ultraviolet) curing printing ink and preparation method thereof 东莞市嘉宝材料科技有限公司 2025-06-13 CN claimed
CN-120082231-A Weather-resistant deformation-resistant heavy-duty anticorrosive coating system 深圳市希顺有机硅科技有限公司 2025-06-03 CN claimed
US-4273865-A Insolubilized biochemical materials BYK-MALLINCKRODT CHEMISCHE PRODUKTE GMBH (DE) 1981-06-16 US claimed
US-4228092-A BY ALCOHOL ESTERIFICATION DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-10-14 US claimed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US claimed
US-4127598-A ADSORPTION WITH A MOLECULAR SIEVE OR CHARCOAL MCENTEE HARRY R 1978-11-28 US claimed
US-4061844-A AMINOALKYL ACRYLATE COPOLYMER, SILICON OR TIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-12-06 US claimed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US claimed
US-3980686-A Process for the preparation of chlorosilane RHONE-POULENC INDUSTRIES (FR) 1976-09-14 US claimed
US-3962299-A Organopolysiloxane polyesters CELANESE CORPORATION (US) 1976-06-08 US claimed
US-3951853-A AMIDE, REACTION PRODUCT OF A HALOSILANE AND A BASE DIAMOND SHAMROCK CORPORATION (US) 1976-04-20 US claimed
US-3939195-A Preparation of silanol containing organopolysiloxanes BAYER AKTIENGESELLSCHAFT (DT) 1976-02-17 US claimed