Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120692 | 0.94 | TSHR (0.39) | ESR1ESR2TSHRLMNAALOX12 | |
| SCHEMBL76000 | 0.94 | TSHR (0.39) | ESR1ESR2TSHRLMNAALOX12 | |
| Fluoride SCHEMBL5604818 | 0.90 | TSHR (0.37) | ESR1ESR2TSHRLMNAALOX12 | |
| SCHEMBL705847 | 0.90 | ESR1 (0.40) | ESR1ESR2TSHRNR1H2NR1H3 | |
| SCHEMBL9359904 | 0.86 | ESR1 (0.39) | ESR1ESR2TSHRNR1H2NR1H3 | |
| Toluene SCHEMBL28546934 | 0.86 | ACHE (0.58) | ESR1ESR2TSHRLMNAALOX12 | |
| SCHEMBL5065485 | 0.86 | ESR1 (0.34) | ESR1ESR2TSHRLMNAALOX12 | |
| SCHEMBL28518241 | 0.85 | TSHR (0.33) | ESR1ESR2TSHRALDH1A1HSD17B10 | |
| SCHEMBL9586411 | 0.85 | TSHR (0.33) | ESR1ESR2TSHRALDH1A1HSD17B10 | |
| SCHEMBL3482589 | 0.84 | ACHE (0.48) | ESR1ESR2TSHRLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659828-A | Method for chlorinating methyl phenyl dichloro-silane | UNIV JIANGSU | 2012-09-12 | — | — | CN | disclosed |