Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065501 | 1.00 | EGFR (0.46) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL13928911 | 0.84 | MEN1 (0.65) | ALDH1A1MEN1KMT2AMAPK1HBB | |
| SCHEMBL4910722 | 0.84 | MEN1 (0.65) | ALDH1A1MEN1KMT2AMAPK1HBB | |
| SCHEMBL5065503 | 0.83 | EGFR (0.46) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL13749328 | 0.83 | ENPP1 (0.53) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL13723744 | 0.81 | ENPP1 (0.57) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL8444902 | 0.79 | MEN1 (0.64) | MEN1KMT2AMAPK1HBB | |
| SCHEMBL13724155 | 0.78 | MEN1 (0.65) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL14986937 | 0.77 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPK1HBB | |
| Hydrochloric Acid SCHEMBL4095590 | 0.76 | MAPK1 (0.64) | EGFRADORA2AENPP1NT5EPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | ALT SOLUTIONS, INC. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | TERT, POLRMT, RNASE1 | EGFR 2253/4885ADORA2A 1461/4885ENPP1 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.