Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | POLG | P54098 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724155 | 0.90 | MEN1 (0.65) | ENPP1NT5EMEN1KMT2AMAPK1 | |
| SCHEMBL13749328 | 0.89 | ENPP1 (0.53) | ENPP1NT5EMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL4095590 | 0.88 | MAPK1 (0.64) | ENPP1NT5EMEN1KMT2AMAPK1 | |
| SCHEMBL9426463 | 0.86 | ENPP1 (0.61) | ENPP1NT5EMEN1KMT2AADORA2A | |
| SCHEMBL5065501 | 0.81 | EGFR (0.46) | ENPP1NT5EMEN1KMT2AMAPK1 | |
| SCHEMBL4089586 | 0.81 | EGFR (0.46) | ENPP1NT5EMEN1KMT2AMAPK1 | |
| SCHEMBL4094131 | 0.79 | EGFR (0.64) | ENPP1NT5EADORA2AADORA1ALDH1A1 | |
| SCHEMBL5065503 | 0.79 | EGFR (0.46) | ENPP1NT5EMEN1KMT2AMAPK1 | |
| SCHEMBL2293269 | 0.78 | ADORA2A (0.66) | ENPP1NT5EHBBADORA2AADORA1 | |
| SCHEMBL20096689 | 0.78 | ADORA2A (0.66) | ENPP1NT5EADORA2AADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | ALT SOLUTIONS, INC. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | TERT, POLRMT, RNASE1 | ENPP1 214/4885NT5E 523/4885MEN1 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.