Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.61 |
| ▸ | PI4KA | P42356 | 3/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.61 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.61 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 3/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096602 | 0.82 | ADORA2A (0.54) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4096596 | 0.81 | ADORA2A (0.58) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4094994 | 0.80 | ADORA2A (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11247503 | 0.78 | ENPP1 (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20096700 | 0.78 | ADORA2A (0.64) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10566016 | 0.77 | ENPP1 (0.59) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2293269 | 0.77 | ADORA2A (0.66) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20096689 | 0.77 | ADORA2A (0.66) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| 9-Benzyl-9H-Adenine SCHEMBL104932 | 0.76 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4094131 | 0.76 | EGFR (0.64) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | ALT SOLUTIONS, INC. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | TERT, POLRMT, RNASE1 | ADORA2A 1461/4885PI4KA 3172/4885PI4K2B 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.