Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501140 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1APEX1CA12CA9 | |
| SCHEMBL11007720 | 0.68 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL27451981 | 0.68 | ALDH1A1 (0.34) | SMN1; SMN2L3MBTL1APEX1CA12CA9 | |
| SCHEMBL7062477 | 0.68 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1APEX1ACEDPP4 | |
| SCHEMBL7058422 | 0.68 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1APEX1ACEDPP4 | |
| SCHEMBL27287079 | 0.67 | TSHR (0.36) | SMN1; SMN2L3MBTL1APEX1CA12CA9 | |
| SCHEMBL6347888 | 0.62 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1ACE | |
| SCHEMBL11513013 | 0.62 | — | — | |
| SCHEMBL28187140 | 0.60 | SMN1; SMN2 (0.30) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL1133635 | 0.59 | P2RX4 (0.41) | SMN1; SMN2APEX1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1639080-A4 | A LIBRARY OF PHYLOGENETICALLY RELATED SEQUENCES | COGNETIX INC (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1639080-A2 | A LIBRARY OF PHYLOGENETICALLY RELATED SEQUENCES | Cognetix, Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108901-A2 | A LIBRARY OF PHYLOGENETICALLY RELATED SEQUENCES | COGNETIX, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040248189-A1 | Method of making a library of phylogenetically related sequences | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-09 | — | — | US | disclosed |